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Generation of a Syngeneic Heterozygous ACVRL1(wt/mut) Knockout iPS Cell Line for the In Vitro Study of HHT2-Associated Angiogenesis
Hereditary hemorrhagic telangiectasia (HHT) type 2 is an autosomal dominant disease in which one allele of the ACVRL1 gene is mutated. Patients exhibit disturbances in TGF-beta/BMP-dependent angiogenesis and, clinically, often present with severe nosebleeds as well as a reduced quality of life. The...
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| Autors principals: | , , , , , , , , , , |
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| Format: | Article |
| Idioma: | anglès |
| Publicat: |
Philipps-Universität Marburg
2023
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| Matèries: | |
| Accés en línia: | PDF a text complet |
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Publikationen im Open Access gefördert durch die UB