Rhabdomyolysis in children in acute and chronic disease - a challenging condition in pediatric emergency medicine

Rhabdomyolysis in children in acute and chronic disease - a challenging condition in pediatric emergency medicine

Rhabdomyolysis is a challenging condition in pediatric emergency departments (PED): It ranges from asymptomatic illness with isolated elevation of creatine kinase (CK) levels to a life-threatening condition associated with extreme elevations in CK, electrolyte imbalances, circulatory failure (CF), a...

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Principais autores: Mand, Nadine, Donath, Carolin, Leonhardt, A., Weber, S., Kömhoff, Martin
Formato: Artigo
Idioma:inglês
Publicado em: Philipps-Universität Marburg 2023
Assuntos:
circulatory failure
rhabdomyolysis
hereditary metabolic disease
LPIN1 mutation
Medizin
acute kidney injury (AKI)
Medical sciences Medicine
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Resumo:Rhabdomyolysis is a challenging condition in pediatric emergency departments (PED): It ranges from asymptomatic illness with isolated elevation of creatine kinase (CK) levels to a life-threatening condition associated with extreme elevations in CK, electrolyte imbalances, circulatory failure (CF), acute kidney injury (AKI), and multi-organ disease. Most common causes of rhabdomyolysis are viral myositis and trauma, hereditary metabolic myopathies must be considered when facing rhabdomyolysis in early childhood. We report two cases of severe rhabdomyolysis with CF in our PED, thereby summarizing first-line management of rhabdomyolysis.
Descrição do item:Gefördert durch den Open-Access-Publikationsfonds der UB Marburg.
DOI:10.3389/fped.2023.1070465

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