Rhabdomyolysis in children in acute and chronic disease - a challenging condition in pediatric emergency medicine

Rhabdomyolysis in children in acute and chronic disease - a challenging condition in pediatric emergency medicine

Rhabdomyolysis is a challenging condition in pediatric emergency departments (PED): It ranges from asymptomatic illness with isolated elevation of creatine kinase (CK) levels to a life-threatening condition associated with extreme elevations in CK, electrolyte imbalances, circulatory failure (CF), a...

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Autores principales: Mand, Nadine, Donath, Carolin, Leonhardt, A., Weber, S., Kömhoff, Martin
Formato: Artículo
Lenguaje:inglés
Publicado: Philipps-Universität Marburg 2023
Materias:
circulatory failure
rhabdomyolysis
hereditary metabolic disease
LPIN1 mutation
Medizin
acute kidney injury (AKI)
Medical sciences Medicine
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Sumario:Rhabdomyolysis is a challenging condition in pediatric emergency departments (PED): It ranges from asymptomatic illness with isolated elevation of creatine kinase (CK) levels to a life-threatening condition associated with extreme elevations in CK, electrolyte imbalances, circulatory failure (CF), acute kidney injury (AKI), and multi-organ disease. Most common causes of rhabdomyolysis are viral myositis and trauma, hereditary metabolic myopathies must be considered when facing rhabdomyolysis in early childhood. We report two cases of severe rhabdomyolysis with CF in our PED, thereby summarizing first-line management of rhabdomyolysis.
Notas:Gefördert durch den Open-Access-Publikationsfonds der UB Marburg.
DOI:10.3389/fped.2023.1070465

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