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TLR7 and IgM: Dangerous Partners in Autoimmunity
The B cell antigen receptor (BCR)-repertoire is capable of recognizing a nearly unlimited number of antigens. Inevitably, the random nature of antibody gene segment rearrangement, needed in order to provide mature B cells, will generate autoreactive specificities. Once tolerance mechanisms fail to b...
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| Autoren: | , |
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| Formato: | Artigo |
| Idioma: | inglês |
| Publicado em: |
Philipps-Universität Marburg
2022
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| Assuntos: | |
| Acesso em linha: | Texto integral em PDF |
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