Pharmacological modulation of myeloid-derived suppressor cells to dampen inflammation

Pharmacological modulation of myeloid-derived suppressor cells to dampen inflammation

Myeloid-derived suppressor cells (MDSCs) are a heterogeneous cell population with potent suppressive and regulative properties. MDSCs’ strong immunosuppressive potential creates new possibilities to treat chronic inflammation and autoimmune diseases or induce tolerance towards transplantation. Here,...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: van Geffen, Chiel, Heiss, Constantin, Deißler, Astrid, Kolahian, Saeed
Hōputu: Tuhinga
Reo:Ingarihi
I whakaputaina: Philipps-Universität Marburg 2022
Ngā marau:
MDSC
immune suppression
pharmacotherapy
immunomodulation
inflammation
Medizin
Medical sciences Medicine
Urunga tuihono:Kuputuhi katoa PDF
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Whakaahuatanga
Whakarāpopototanga:Myeloid-derived suppressor cells (MDSCs) are a heterogeneous cell population with potent suppressive and regulative properties. MDSCs’ strong immunosuppressive potential creates new possibilities to treat chronic inflammation and autoimmune diseases or induce tolerance towards transplantation. Here, we summarize and critically discuss different pharmacological approaches which modulate the generation, activation, and recruitment of MDSCs in vitro and in vivo, and their potential role in future immunosuppressive therapy.
Whakaahutanga tūemi:Gefördert durch den Open-Access-Publikationsfonds der UB Marburg.
DOI:10.3389/fimmu.2022.933847

Ngā tūemi rite