Reciprocal Regulation of MAGED2 and HIF-1α Augments Their Expression under Hypoxia: Role of cAMP and PKA Type II

Seaayfan, Elie; Nasrah, Sadiq; Quell, Lea; Radi, Aline; Kleim, Maja; Schermuly, Ralph T.; Weber, Stefanie; Laghmani, Kamel; Kömhoff, Martin

Reciprocal Regulation of MAGED2 and HIF-1α Augments Their Expression under Hypoxia: Role of cAMP and PKA Type II

Hypoxia stabilizes the transcription factor HIF-1α, which promotes the transcription of many genes essential to adapt to reduced oxygen levels. Besides proline hydroxylation, expression of HIF-1α is also regulated by a range of other posttranslational modifications including phosphorylation by cAMP-...

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Autoren:	Seaayfan, Elie, Nasrah, Sadiq, Quell, Lea, Radi, Aline, Kleim, Maja, Schermuly, Ralph T., Weber, Stefanie, Laghmani, Kamel, Kömhoff, Martin
Format:	Artikel
Jezik:	angleščina
Izdano:	Philipps-Universität Marburg 2022
Teme:	hypoxia HIF-1α MAGED2 Medizin PKA type II Bartter GalphaS Medical sciences Medicine
Online dostop:	PDF-Volltext
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Reciprocal Regulation of MAGED2 and HIF-1α Augments Their Expression under Hypoxia: Role of cAMP and PKA Type II

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