Enhanced firing of locus coeruleus neurons and SK channel dysfunction are conserved in distinct models of prodromal Parkinson’s disease

Matschke, Lina A.; Komadowski, Marlene A.; Stöhr, Annette; Lee, Bolam; Henrich, Martin T.; Griesbach, Markus; Rinné, Susanne; Geibl, Fanni F.; Chiu, Wei-Hua; Koprich, James B.; Brotchie, Jonathan M.; Kiper, Aytug K.; Dolga, Amalia M.; Oertel, Wolfgang H.; Decher, Niels

Enhanced firing of locus coeruleus neurons and SK channel dysfunction are conserved in distinct models of prodromal Parkinson’s disease

Parkinson’s disease (PD) is clinically defined by the presence of the cardinal motor symptoms, which are associated with a loss of dopaminergic nigrostriatal neurons in the substantia nigra pars compacta (SNpc). While SNpc neurons serve as the prototypical cell-type to study cellular vulnerability i...

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Autoren:	Matschke, Lina A., Komadowski, Marlene A., Stöhr, Annette, Lee, Bolam, Henrich, Martin T., Griesbach, Markus, Rinné, Susanne, Geibl, Fanni F., Chiu, Wei-Hua, Koprich, James B., Brotchie, Jonathan M., Kiper, Aytug K., Dolga, Amalia M., Oertel, Wolfgang H., Decher, Niels
格式:	Artikel
語言:	英语
出版:	Philipps-Universität Marburg 2022
主題:	Medizin Medical sciences Medicine
在線閱讀:	PDF-Volltext
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Enhanced firing of locus coeruleus neurons and SK channel dysfunction are conserved in distinct models of prodromal Parkinson’s disease

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