Effect of chronic intermittent hypoxia (CIH) on neuromuscular junctions and mitochondria in slow- and fast-twitch skeletal muscles of mice - the role of iNOS

Effect of chronic intermittent hypoxia (CIH) on neuromuscular junctions and mitochondria in slow- and fast-twitch skeletal muscles of mice - the role of iNOS

Background: Obstructive sleep apnea (OSA) imposes vascular and metabolic risks through chronic intermittent hypoxia (CIH) and impairs skeletal muscle performance. As studies addressing limb muscles are rare, the reasons for the lower exercise capacity are unknown. We hypothesize that CIH-related m...

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Autoren: Bannow, L. I., Bonaterra, G. A., Bertoune, M., Maus, S., Schulz, R., Weissmann, N., Kraut, S., Kinscherf, R., Hildebrandt, W.
Format: Artikel
Sprache:Englisch
Veröffentlicht: Philipps-Universität Marburg 2022
Schlagworte:
Oxidative stress
Denervation
iNOS
Muscle atrophy
Fiber type
Mitochondria
Neuromuscular junction
Medizin
Medical sciences Medicine
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