MAGED2 Is Required under Hypoxia for cAMP Signaling by Inhibiting MDM2-Dependent Endocytosis of G-Alpha-S

MAGED2 Is Required under Hypoxia for cAMP Signaling by Inhibiting MDM2-Dependent Endocytosis of G-Alpha-S

Mutations in MAGED2 cause transient Bartter syndrome characterized by severe renal salt wasting in fetuses and infants, which leads to massive polyhydramnios causing preterm labor, extreme prematurity and perinatal death. Notably, this condition resolves spontaneously in parallel with developmental...

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Bibliográfalaš dieđut
Váldodahkkit: Seaayfan, Elie, Nasrah, Sadiq, Quell, Lea, Kleim, Maja, Weber, Stefanie, Meyer, Hemmo, Laghmani, Kamel, Kömhoff, Martin
Materiálatiipa: Artihkal
Giella:eaŋgalasgiella
Almmustuhtton: Philipps-Universität Marburg 2022
Fáttát:
MAGED2
Medizin
G-alpha-S
MDM2
Bartter
hypoxia
Medical sciences Medicine
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oažžasuvvan:
Hildobáiki: urn:nbn:de:hebis:04-es2023-00501
Almmustuhttinbeaivi: 2023-05-16
Gáldu: Erstveröffentlichung: Seaayfan, E.; Nasrah, S.; Quell, L.; Kleim, M.;Weber, S.; Meyer, H.; Laghmani, K.; Kömhoff, M. MAGED2 Is Required under Hypoxia for cAMP Signaling by Inhibiting MDM2-Dependent Endocytosis of G-Alpha-S. Cells 2022, 11, 2546. https://doi.org/10.3390/cells11162546
Downloads: 27 (2024), 63 (2023)
Lizenz: https://creativecommons.org/licenses/by/4.0
Liŋka materiálii: https://archiv.ub.uni-marburg.de/es/2023/0050
https://doi.org/10.3390/cells11162546

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