MAGED2 Is Required under Hypoxia for cAMP Signaling by Inhibiting MDM2-Dependent Endocytosis of G-Alpha-S

MAGED2 Is Required under Hypoxia for cAMP Signaling by Inhibiting MDM2-Dependent Endocytosis of G-Alpha-S

Mutations in MAGED2 cause transient Bartter syndrome characterized by severe renal salt wasting in fetuses and infants, which leads to massive polyhydramnios causing preterm labor, extreme prematurity and perinatal death. Notably, this condition resolves spontaneously in parallel with developmental...

Whakaahuatanga katoa

I tiakina i:
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Ngā kaituhi matua: Seaayfan, Elie, Nasrah, Sadiq, Quell, Lea, Kleim, Maja, Weber, Stefanie, Meyer, Hemmo, Laghmani, Kamel, Kömhoff, Martin
Hōputu: Tuhinga
Reo:Ingarihi
I whakaputaina: Philipps-Universität Marburg 2022
Ngā marau:
MAGED2
Medizin
G-alpha-S
MDM2
Bartter
hypoxia
Medical sciences Medicine
Urunga tuihono:Kuputuhi katoa PDF
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