Transient reduction in dendritic spine density in brain-specific profilin1 mutant mice is associated with behavioral deficits

Transient reduction in dendritic spine density in brain-specific profilin1 mutant mice is associated with behavioral deficits

Actin filaments form the backbone of dendritic spines, the postsynaptic compartment of most excitatory synapses in the brain. Spine density changes affect brain function, and postsynaptic actin defects have been implicated in various neuropathies. It is mandatory to identify the actin regulators tha...

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Autoren: Sungur, A. Özge, Zeitouny, Caroline, Gabele, Lea, Metz, Isabell, Wöhr, Markus, Michaelsen-Preusse, Kristin, Rust, Marco B.
Format: Artikel
Sprache:Englisch
Veröffentlicht: Philipps-Universität Marburg 2023
Schlagworte:
social recognition
actin dynamics
ultrasonic vocalization
spine morphology
Medizin
memory formation
object recognition
Medical sciences Medicine
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