Rezultati - Klebe, Gerhard

Crystallographic Fragment Screening on the Shigella Type III Secretion System Chaperone IpgC od Gárdonyi, Marina, Hasewinkel, Christian, Wallbaum, Johanna, Wollenhapt, Jan, Weiss, Manfred S., Klebe, Gerhard, Reuter, Klaus, Heine, Andreas

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Leitstruktursuche mithilfe eines kristallographischen Fragment-Screenings zur Inhibierung des Klasse-II-Chaperons IpgC aus Shigella flexneri od Gárdonyi, Marina

Drugi avtorji: “...Klebe, Gerhard (Prof. Dr.)...”
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Optimization of the Drug Design Process by Ligand Preorganization and Occupancy of Transient Binding Pockets Based on the Model Proteins Thrombin and Aldose Reductase od Sandner, Anna Sophie

Drugi avtorji: “...Klebe, Gerhard (Prof. Dr.)...”
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Mutational Studies on 17β-HSD14, Serial Synchrotron X-ray Crystallography, Solubility Enhancement using Cyclodextrins and Fragment-Based Drug Discovery Multiple Blocks to Pave the... od Badran, Mohammed

Drugi avtorji: “...Klebe, Gerhard (Prof. Dr.)...”
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Neue Ansätze zur Entwicklung von Modulatoren der homodimeren tRNA-Guanin-Transglycosylase od Nguyen, Andreas

Drugi avtorji: “...Klebe, Gerhard (Prof. Dr.)...”
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Fragment-basierte Leitstruktursuche am Beispiel der Proteinkinase A od Oebbeke, Matthias

Drugi avtorji: “...Klebe, Gerhard (Prof. Dr.)...”
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From Serendipity to the Rational Design of Protein–Protein Interface Modulators Targeting a tRNA-Modifying Enzyme od Nguyen, Dzung

Drugi avtorji: “...Klebe, Gerhard (Prof. Dr.)...”
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Thermodynamic, Kinetic and Crystallographic Investigations of Benzenesulfonamides as Ligands of Human Carbonic Anhydrase II od Glöckner, Steffen

Drugi avtorji: “...Klebe, Gerhard Prof. Dr....”
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Do All Roads Really Lead to Rome? Learnings from Comparative Analysis using SPR, NMR, & X-Ray Crystallography to Optimize Fragment Screening in Drug Discovery. od Hassaan, Engi

Drugi avtorji: “...Klebe, Gerhard (Prof. Dr.)...”
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Synthese von D-Phe/D-DiPhe-Pro-basierenden Liganden und deren biophysikalischen Charakterisierung zur Selektivitätsstudie von Thrombin und Trypsin sowie ein synthetischer Beitrag z... od Ngo, Trong Khang

Drugi avtorji: “...Klebe, Gerhard (Prof. Dr.)...”
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Targeting farnesyl pyrophosphate synthase of Trypanosoma cruzi by fragment-based lead discovery od Petrick, Joy Kristin

Drugi avtorji: “...Klebe, Gerhard (Prof. Dr.)...”
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Targeting Trypanosoma brucei FPPS by Fragment-based drug discovery od Münzker Lena

Drugi avtorji: “...Klebe, Gerhard (Prof. Dr.)...”
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The Power of Fragments: FBLD approach to investigate protein structures od Magari, Francesca

Drugi avtorji: “...Klebe, Gerhard (Prof. Dr.)...”
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Identifizierung, Charakterisierung und Untersuchungen der Struktur-Wirkungs-Beziehung sowie des Mode of Action eines neuen antimikrobiellen Peptids aus Hirudo verbana od Müller, Daniela

Drugi avtorji: “...Klebe, Gerhard (Prof. Dr. rer. nat.)...”
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Expanding the Toolbox for Computational Analysis in Rational Drug Discovery: Using Biomolecular Solvation to Predict Thermodynamic, Kinetic and Structural Properties of Protein-Lig... od Hüfner, Tobias

Drugi avtorji: “...Klebe, Gerhard (Prof. Dr.)...”
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Inhibitor Synthesis and Biophysical Characterization of Protein–Ligand–Solvent Interactions An Analysis of the Thermodynamics and Kinetics of Ligand Binding to Thermolysin od Cramer, Jonathan

Drugi avtorji: “...Klebe, Gerhard (Prof. Dr.)...”
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Characterisation and differentiation of kinase binding pockets in PKA and PIM1 by small molecule fragments using protein crystallography od Siefker, Christof

Drugi avtorji: “...Klebe, Gerhard (Prof. Dr.)...”
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Structural Characterization of 17β-Hydroxysteroid Dehydrogenase Type 14 and Inhibitor Optimization Using Crystallography and Computational Techniques od Bertoletti, Nicole

Drugi avtorji: “...Klebe, Gerhard (Prof. Dr.)...”
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Beyond Affinity: Drug-Kinase Interaction Put under the Microscope od Wienen-Schmidt, Barbara

Drugi avtorji: “...Klebe, Gerhard (Prof.)...”
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Proteindynamik - Flexibilität in Zielproteinen des strukturbasierten Wirkstoffdesigns od Terwesten, Felix

Drugi avtorji: “...Klebe, Gerhard (Prof. Dr.)...”
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