Author Search Results

1

Nichtkompetitive Inhibition der tRNA-Guanin Transglycosylase durch Störung der essentiellen Protein-Protein-Interaktion

by Jakobi, Stephan
Published 2013

Contributors: “...Klebe, Gerhard (Prof. Dr.)...”
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Dissertation

2

Development of models to describe the dynamics and interaction with water molecules in protein-ligand binding

by Betz, Michael
Published 2015

Contributors: “...Klebe, Gerhard (Prof. Dr.)...”
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Dissertation

3

Insights into Protein-Ligand Molecular Recognition: Thermodynamic, Kinetic and Structural Characterization of Inhibitor Binding to Aldose Reductase and Carbonic Anhydrase II

by Rechlin, Chris
Published 2015

Contributors: “...Klebe, Gerhard (Prof. Dr.)...”
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Dissertation

4

Strukturelle und thermodynamische Charakterisierung der Fragment und Liganden Bindung an Thrombin

by Rühmann, Eggert Henning
Published 2015

Contributors: “...Klebe, Gerhard (Prof. Dr.)...”
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Dissertation

5

Investigations on lin-Benzopurines With Respect to Dissociation Behavior, Pocket Cross-Talk, Targeting Resistance Mutants, Residual Mobility, and Scaffold Optimization

by Neeb, Manuel
Published 2014

Contributors: “...Klebe, Gerhard (Prof. Dr.)...”
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Dissertation

6

Proteindynamik - Flexibilität in Zielproteinen des strukturbasierten Wirkstoffdesigns

by Terwesten, Felix
Published 2017

Contributors: “...Klebe, Gerhard (Prof. Dr.)...”
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Dissertation

7

Beschreibung von Proteinbindetaschen für Funktionsstudien und de Novo-Design und die Entwicklung von Methoden zur funktionellen Klassifizierung von Proteinfamilien

by Kuhn, Daniel
Published 2004

Contributors: “...Klebe, Gerhard (Prof. Dr.)...”
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Dissertation

8

Novel Strategies for Model-Building of G Protein-Coupled Receptors

by van Neuren, Anske Stephanie
Published 2003

Contributors: “...Klebe, Gerhard (Prof. Dr.)...”
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Dissertation

9

Concepts to Interfere with Protein-Protein Complex Formations: Data Analysis, Structural Evidence and Strategies for Finding Small Molecule Modulators

by Block, Peter
Published 2005

Contributors: “...Klebe, Gerhard (Prof. Dr.)...”
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Dissertation

10

Systematic Correlation of Structural, Thermodynamic and Residual Solvation Properties of Hydrophobic Substituents in Hydrophobic Pockets Using Thermolysin as a Case Study

by Krimmer, Stefan Günter
Published 2017

Contributors: “...Klebe, Gerhard (Prof. Dr.)...”
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Dissertation

11

Methods for the Efficient Comparison of Protein Binding Sites and for the Assessment of Protein-Ligand Complexes

by Krotzky, Timo
Published 2015

Contributors: “...Klebe, Gerhard (Prof. Dr.)...”
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Dissertation

12

Strukturbasierte Entwicklung und Charakterisierung von Inhibitoren der TGT,ein mögliches Ziel zur Therapie der Bakterienruhr

by Ehrmann, Frederik Rainer
Published 2016

Contributors: “...Klebe, Gerhard (Prof.Dr.)...”
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Dissertation

13

From Active-Site Mapping to Lead Discovery using Fragment-based Approaches on the Aspartic protease Endothiapepsin

by Radeva, Nedyalka
Published 2016

Contributors: “...Klebe, Gerhard (Prof. Dr.)...”
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Dissertation

14

Structural Characterization of 17β-Hydroxysteroid Dehydrogenase Type 14 and Inhibitor Optimization Using Crystallography and Computational Techniques

by Bertoletti, Nicole
Published 2017

Contributors: “...Klebe, Gerhard (Prof. Dr.)...”
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Dissertation

15

17β Hydroxysteroid Dehydrogenase 14 (17β-HSD14): Entwicklung und Synthese potenter und selektiver Inhibitoren zur strukturellen Charakterisierung und Untersuchung der physiologisch...

by Braun, Florian
Published 2017

Contributors: “...Klebe, Gerhard (Prof. Dr.)...”
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Dissertation

16

Röntgenkristallographische Studien von Nukleotidkofaktor-bindenden und tRNA-modifizierenden Enzymen

by Sgraja, Tanja
Published 2004

Contributors: “...Klebe, Gerhard (Prof. Dr.)...”
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Dissertation

17

De novo-Design und Synthese neuer Leitstrukturen als Übergangszustandsmimetika zur selektiven Inhibition der HIV-1 Protease und Cathepsin D

by Specker, Edgar
Published 2004

Contributors: “...Klebe, Gerhard (Prof. Dr.)...”
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Dissertation

18

Kristallstrukturanalyse und Entwicklung von Computermodellen zur Beschreibung der Selektivität von Enzymen am Beispiel der Carboanhydrase

by Weber, Alexander
Published 2004

Contributors: “...Klebe, Gerhard (Prof. Dr.)...”
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Dissertation

19

Characterisation and differentiation of kinase binding pockets in PKA and PIM1 by small molecule fragments using protein crystallography

by Siefker, Christof
Published 2018

Contributors: “...Klebe, Gerhard (Prof. Dr.)...”
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Dissertation

20

Optimiertes Design kombinatorischer Verbindungsbibliotheken durch Genetische Algorithmen und deren Bewertung anhand wissensbasierter Protein-Ligand Bindungsprofile

by Pfeffer, Patrick
Published 2009

Contributors: “...Klebe, Gerhard (Prof. Dr.)...”
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Dissertation

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