Author Search Results

1

Thermodynamic, Kinetic and Crystallographic Investigations of Benzenesulfonamides as Ligands of Human Carbonic Anhydrase II

by Glöckner, Steffen
Published 2020

Contributors: “...Klebe, Gerhard Prof. Dr....”
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Dissertation

2

Do All Roads Really Lead to Rome? Learnings from Comparative Analysis using SPR, NMR, & X-Ray Crystallography to Optimize Fragment Screening in Drug Discovery.

by Hassaan, Engi
Published 2019

Contributors: “...Klebe, Gerhard (Prof. Dr.)...”
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Dissertation

3

Synthese von D-Phe/D-DiPhe-Pro-basierenden Liganden und deren biophysikalischen Charakterisierung zur Selektivitätsstudie von Thrombin und Trypsin sowie ein synthetischer Beitrag z...

by Ngo, Trong Khang
Published 2020

Contributors: “...Klebe, Gerhard (Prof. Dr.)...”
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Dissertation

4

Targeting farnesyl pyrophosphate synthase of Trypanosoma cruzi by fragment-based lead discovery

by Petrick, Joy Kristin
Published 2019

Contributors: “...Klebe, Gerhard (Prof. Dr.)...”
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Dissertation

5

Targeting Trypanosoma brucei FPPS by Fragment-based drug discovery

by Münzker Lena
Published 2019

Contributors: “...Klebe, Gerhard (Prof. Dr.)...”
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Dissertation

6

The Power of Fragments: FBLD approach to investigate protein structures

by Magari, Francesca
Published 2020

Contributors: “...Klebe, Gerhard (Prof. Dr.)...”
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Dissertation

7

Identifizierung, Charakterisierung und Untersuchungen der Struktur-Wirkungs-Beziehung sowie des Mode of Action eines neuen antimikrobiellen Peptids aus Hirudo verbana

by Müller, Daniela
Published 2019

Contributors: “...Klebe, Gerhard (Prof. Dr. rer. nat.)...”
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Dissertation

8

Expanding the Toolbox for Computational Analysis in Rational Drug Discovery: Using Biomolecular Solvation to Predict Thermodynamic, Kinetic and Structural Properties of Protein-Lig...

by Hüfner, Tobias
Published 2019

Contributors: “...Klebe, Gerhard (Prof. Dr.)...”
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Dissertation

9

Inhibitor Synthesis and Biophysical Characterization of Protein–Ligand–Solvent Interactions An Analysis of the Thermodynamics and Kinetics of Ligand Binding to Thermolysin

by Cramer, Jonathan
Published 2017

Contributors: “...Klebe, Gerhard (Prof. Dr.)...”
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Dissertation

10

Characterisation and differentiation of kinase binding pockets in PKA and PIM1 by small molecule fragments using protein crystallography

by Siefker, Christof
Published 2018

Contributors: “...Klebe, Gerhard (Prof. Dr.)...”
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Dissertation

11

Structural Characterization of 17β-Hydroxysteroid Dehydrogenase Type 14 and Inhibitor Optimization Using Crystallography and Computational Techniques

by Bertoletti, Nicole
Published 2017

Contributors: “...Klebe, Gerhard (Prof. Dr.)...”
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Dissertation

12

Proteindynamik - Flexibilität in Zielproteinen des strukturbasierten Wirkstoffdesigns

by Terwesten, Felix
Published 2017

Contributors: “...Klebe, Gerhard (Prof. Dr.)...”
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Dissertation

13

Erkennen von Proteinoberflächen durch ungewöhnliche Substrat-analoge Inhibitoren am Beispiel der cAMP-abhängigen Proteinkinase A

by Müller, Janis
Published 2017

Contributors: “...Klebe, Gerhard (Prof. Dr.)...”
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Dissertation

14

Systematic Correlation of Structural, Thermodynamic and Residual Solvation Properties of Hydrophobic Substituents in Hydrophobic Pockets Using Thermolysin as a Case Study

by Krimmer, Stefan Günter
Published 2017

Contributors: “...Klebe, Gerhard (Prof. Dr.)...”
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Dissertation

15

17β Hydroxysteroid Dehydrogenase 14 (17β-HSD14): Entwicklung und Synthese potenter und selektiver Inhibitoren zur strukturellen Charakterisierung und Untersuchung der physiologisch...

by Braun, Florian
Published 2017

Contributors: “...Klebe, Gerhard (Prof. Dr.)...”
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Dissertation

16

Structure-Based Design of a Blood Coagulation Factor XIII Blocker

by Stieler, Martin
Published 2017

Contributors: “...Klebe, Gerhard (Prof. Dr.)...”
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Dissertation

17

Strukturbasierte Entwicklung und Charakterisierung von Inhibitoren der TGT,ein mögliches Ziel zur Therapie der Bakterienruhr

by Ehrmann, Frederik Rainer
Published 2016

Contributors: “...Klebe, Gerhard (Prof.Dr.)...”
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Dissertation

18

From Active-Site Mapping to Lead Discovery using Fragment-based Approaches on the Aspartic protease Endothiapepsin

by Radeva, Nedyalka
Published 2016

Contributors: “...Klebe, Gerhard (Prof. Dr.)...”
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Dissertation

19

Insights into Protein-Ligand Molecular Recognition: Thermodynamic, Kinetic and Structural Characterization of Inhibitor Binding to Aldose Reductase and Carbonic Anhydrase II

by Rechlin, Chris
Published 2015

Contributors: “...Klebe, Gerhard (Prof. Dr.)...”
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Dissertation

20

Development of models to describe the dynamics and interaction with water molecules in protein-ligand binding

by Betz, Michael
Published 2015

Contributors: “...Klebe, Gerhard (Prof. Dr.)...”
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Dissertation

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