Dokument
| Titel: | Insights into Protein-Ligand Molecular Recognition: Thermodynamic, Kinetic and Structural Characterization of Inhibitor Binding to Aldose Reductase and Carbonic Anhydrase II |
| Autor: | Rechlin, Chris |
| Weitere Beteiligte: | Klebe, Gerhard (Prof. Dr.) |
| Veröffentlicht: | 2015 |
| URI: | https://archiv.ub.uni-marburg.de/diss/z2015/0464 |
| URN: | urn:nbn:de:hebis:04-z2015-04648 |
| DOI: | https://doi.org/10.17192/z2015.0464 |
| DDC: | 610 Medizin |
| Titel (trans.): | Einblicke in die Protein-Ligand Erkennung: Thermodynamische, Kinetische und Strukturelle Charakterisierung der Inhibitor Bindung an die Aldose Reduktase und Carboanhydrase II |
| Publikationsdatum: | 2016-11-10 |
| Lizenz: | https://rightsstatements.org/vocab/InC-NC/1.0/ |
| Schlagwörter: |
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| Thermodynamic, Ligand, Kinetic, Drug Design, Ligand, Proteins, Kinetik, Thermodynamik, Arzneimitteldesign, Proteine |
Summary:
Two pathological relevant proteins, human aldose reductase and human carbonic anhydrase, were used as model proteins to get insights into the process of molecular recognition. The thermodynamics and kinetics of the formation process of protein ligand complex formation were studied.
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