Nichtkompetitive Inhibition der tRNA-Guanin Transglycosylase durch Störung der essentiellen Protein-Protein-Interaktion

Protein-Protein-Kontakte stellen eine reiche Vielfalt an Interaktionsmöglichkeiten der Polypeptide mit regulatorischen Funktionen innerhalb lebender Organismen dar. Das homodimere Enzym tRNA-Guanin Transglykosylase(TGT) katalysiert z. B. eine Basenaustauschreaktion, die essentiell für die Pathogeni...

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1. Verfasser: Jakobi, Stephan
Beteiligte: Klebe, Gerhard (Prof. Dr.) (BetreuerIn (Doktorarbeit))
Format: Dissertation
Sprache:Deutsch
Veröffentlicht: Philipps-Universität Marburg 2013
Pharmazeutische Chemie
Ausgabe:http://dx.doi.org/10.17192/z2013.0380
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1. http://archiv.ub.uni-marburg.de/diss/z2010/0356


2. http://archiv.ub.uni-marburg.de/diss/z2014/0178


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