Synthese und Charakterisierung von Inhibitoren der hämagglutininspaltenden Proteasen Furin und HAT

In der vorliegenden Arbeit wurden Inhibitoren der hämagglutininspaltenden Proteasen Furin und HAT synthetisiert und charakterisiert. Während die Proproteinkonvertase Furin das Hämagglutinin (HA) hochpathogener Influenzaviren vom Subtyp H5 und H7 aktiviert, bewirkt die trypsinartige Serinprotease HAT...

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1. Verfasser: Sielaff, Frank
Beteiligte: Steinmetzer, Torsten (Prof. Dr. ) (BetreuerIn (Doktorarbeit))
Format: Dissertation
Veröffentlicht: Philipps-Universität Marburg 2011
Pharmazeutische Chemie
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