Zusammenfassung:
In der vorliegenden Dissertation wird die Synthese der neuartigen,
disulfid-verbrückten, bioabbaubaren PEG-PEI-Copolymeren als nicht-virale Vektoren
zur Gentherapie beschrieben. Die DNA-Polyplexe der Copolymere wurden
charakterisiert und auf ihre Eignung als Genvektoren für die in-vivo-Anwendung
untersucht
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